NIH R01 · 2024
MS Diagnostic Bacterial Identification Library
PROJECT SUMMARY Infectious diseases have a substantial global health impact. Clinicians need rapid and accurate diagnoses of infections to direct patient treatment and improve antibiotic stewardship, but current methodologies face severe limitations in this regard. In the first funding cycle of our MPI grant “GM111066 - MS diagnostic bacterial identification library,” we produced a novel diagnostic platform in which microbial membrane glycolipids analyzed by mass spectrometry represent chemical “fingerprints” that were then used to differentiate Gram- negative and –positive and fungal isolates after mono- or poly-microbial growth in standard laboratory medias or complex biological (urine,…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.