Erickson Lab

University of Chicago

PSYCHIATRY

Chicago · United States

NIH-funded
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NIH R01 · 2024

Measurement and manipulation of oscillatory biomarker of working memory in psychosis

Project Summary Although it is widely known that people with psychosis (PSY) exhibit impairment in a number of cognitive domains—and working memory (WM) in particular—interventions aimed at remediating these deficits have been only modestly successful, and mixed results continue to emerge. One critical barrier to increasing the effectiveness of these interventions is the lack of clarity regarding neurobiological mechanisms that give rise to these impairments, and that can be used as treatment targets for intervention development. We suggest that one reason for this lack of clarity is that WM is frequently studied as a unitary phenomenon, when in fact it is dependent upon several cognitive…

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