NIH R01 · 2024
Reproducibility in simulation-based prediction of natural knee mechanics
PROJECT SUMMARY Simulations of knee biomechanics are increasingly utilized to develop individualized and actionable knowledge regarding healthy homeostasis, impact of musculoskeletal diseases, and risk of injury. Computational modeling is also appealing to predict performance and safety of implants, and informs surgical tissue reconstruction and rehabilitation strategies. This is a natural result of the ubiquity of modeling and simulation in biomedicine, and it is motivated by the knee being a primary concern in musculoskeletal healthcare. However, start-to-end and turn- key examples of mechanistic simulations, to accelerate biomedical discovery and to routinely inform clinical care, are…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.