NIH R01 · 2025
Periodontal Disease and Small Vulnerable Newborns: A Cluster Randomized Trial
In 2022, 2.3 million newborns died in their first 28 days of life. Over half of these deaths occurred among small vulnerable newborns (SVN), who are born preterm (<37 weeks’ gestation), small-for-gestational-age (SGA, <10% centile), and/or low birth weight (LBW, <2,500g). The highest rates of SVNs occur in South Asia, where 52.1% of newborns are affected, and global and regional progress in reducing these outcomes has stagnated over the last decade. Periodontal disease has been implicated in observational studies as a factor associated with preterm, SGA, and LBW births. Yet randomized controlled trials evaluating the impact of periodontal interventions on incidence of SVN types have…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.