NIH R01 · 2024
IDENTIFICATION OF COMMON GENETIC VARIANTS FOR ATRIAL FIBRILLATION AND PR INTERVAL
Abstract Atrial fibrillation (AF) is of major public health importance because of increasing prevalence, and high lifetime risk, costs, morbidity, and mortality. Current AF therapies have partial efficacy, moderate adherence, high cost, and substantial morbidity. Hence, there is a profound need to develop a more comprehensive understanding of the etiology of AF to identify individuals at risk for AF and novel drug targets for AF therapies. In 2008, we organized the AFGen Consortium (AFGen) and since that time our highly collaborative, international consortium has led the field of AF genetics. We have described the vast majority of the more than 130 genetic loci that have been associated…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.