Elfar Lab

University of Arizona

ORTHOPEDICS

Tucson · United States

NIH-funded
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Research focus

NIH R01 · 2024

A Single Dose Pharmaco-Diagnostic for Peripheral Nerve Continuity After Trauma

Nerve injury can affect anyone and carries consequences that last forever, and traumatic peripheral nerve injury (TPNI) can result from settings as diverse as battlefield or motor vehicle trauma, to iatrogenic injury from surgical treatments of other serious conditions. For other tissue types, the prognosis and treatment plan are straightforward. However, when nerves fail, doctors have few tools to help guide the treatment plan and patients forever remember their experiences with pain and paralysis. If nerve injuries can happen from many causes, what is the determinant that most predicts a good outcome? The answer is nerve continuity. A nerve that has been severed, say by a bullet will…

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