El-Shamayleh Lab

Columbia University Health Sciences

NEUROSCIENCES

New York · United States

NIH-funded
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NIH R01 · 2024

Cortical circuit mechanisms of visual shape processing

PROJECT SUMMARY Humans and other primates rely on using visual shape information to identify and interact with objects in the world. The goal of this project is to gain mechanistic insights into how the primate cerebral cortex processes visual shape information. Cortical area V4 is an ideal locus for these mechanistic studies because many V4 neurons are tuned for visual shape, showing preferences for convex or concave segments along an object's bounding contour. This tuning for visual shape is presumed to be a foundation for behaviorally relevant object representations, but we know little about its mechanistic implementation. Chiefly, we do not know which cortical pathways and cell types…

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