Eggebrecht Lab

Washington University

OTHER HEALTH PROFESSIONS

Saint Louis · United States

NIH-funded
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NIH R01 · 2025

Interhemispheric Communication and Compensation in Peripheral Nerve Injury

Use of the non-dominant left hand is critical for individuals who suffer chronic impairment of the dominant right hand due to unilateral conditions such as peripheral nerve injury. (This project will study right-handed individuals, and thus uses "right hand" instead of "dominant hand.") Most rehabilitation focuses on restoration of function, but many patients never achieve this: 64,000 people per year in the USA have nerve injury to the right hand but achieve satisfactory recovery, and these patients must learn to compensate by using the left hand. However, the neural mechanisms of left hand compensation remain unknown. Our preliminary data suggest that compensation involves…

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