Efimov Lab

Northwestern University at Chicago

NONE

Chicago · United States

NIH-funded
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Research focus

NIH R01 · 2025

Epicardial high-definition electrotherapy of AFib

Project Summary Paroxysmal atrial fibrillation (AF) is expected to affect 16 million Americans in 2050. AF is a heavy burden on the healthcare system. The current treatment strategies for AF include catheter ablation, transthoracic cardioversion, and drug therapy. Currently, no method exists for painless and rapid conversion of atrial fibrillation. This proposal features a novel epicardial high- resolution organ conformal electronics low-energy atrial defibrillator for painless AF conversion. In this project, a human-scale, fully implantable organ conformal device for high-definition detection and therapy of AF will be developed. It will be tested and optimized on a large animal model: a…

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