Eckert Lab

Medical University of South Carolina

OTOLARYNGOLOGY

Charleston · United States

NIH-funded
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NIH R01 · 2024

Multi-site Study of Dyslexia

ABSTRACT Children from adverse developmental environments demonstrate varied reading achievement. The overarching hypothesis of the proposed research is that genetic and neural canalization provide a buffer against the negative impacts of developmental risks to ensure normative reading and language achievement. Specific Aim 1 tests the hypothesis that genetic canalization protects against the well-established negative effects of low socioeconomic status on written and oral language development. We focus on the polygenic and environmental interactions to characterize canalization, including the extent to which the prevalence of low written and oral language achievement decreases with…

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