Ebelt Lab

Emory University

PUBLIC HEALTH & PREV MEDICINE

Atlanta · United States

NIH-funded
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NIH R01 · 2025

Heat and Acute Kidney Injury: A Detailed Assessment using Electronic Medical Records and High-Resolution Exposure Modeling

Acute kidney injury (AKI) is a sudden decrease of kidney function that is almost always reversible. While reversible, AKI is serious and often requires hospitalization. The economic burden is also substantial at $5-24 billion annually in the US. Although AKI can arise within already-hospitalized patients (“hospital-acquired AKI”), an unknown proportion of AKI initiates outside of the hospital (“community-acquired AKI”). One potential contributor to community-acquired AKI is exposure to high temperatures, which is thought to impact kidneys largely through volume depletion. Studies using administrative health data have consistently reported positive associations between outdoor heat (high…

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