NIH R01 · 2024
Exploring networks underlying muscle stem cell identity - Resubmission - 1
Project Summary Muscle stem cells, also known as satellite cells (SC), are a progenitor population required to replenish muscle damaged by exercise or wasting caused by disease or aging. The ability to generate muscle progenitors from embryonic stem cells (ESC) would represent a major advance in regenerative medicine. However, despite recent progress, it remains very challenging to differentiate mouse and human ESC into muscle progenitors, and SC represent a very small population within muscle tissue. These limitations have significantly hampered progress toward understanding muscle stem cells, and the critical regulatory processes that govern SC identity. The transcription factor, Pax7,…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.