NIH R01 · 2025
Genomics-guided sleep biomarker discovery for early Alzheimer's disease: A wearables study
PROJECT SUMMARY This proposal is responsive to NIA solicitation PAR-22-093/NOT-AG-21-048 for projects involving the development of digital technology for the early detection of Alzheimer’s disease. It is motivated by the need for novel low-cost and noninvasive digital biomarkers for Alzheimer’s disease that can flag early changes in at-risk individuals before cognitive symptoms surface. Changes in sleep patterns have been linked to a future dementia diagnosis in older adults. These changes can be tracked in a passive and unobtrusive way using a wide variety of low-cost consumer wearables. Our overarching objective is to deploy cutting-edge wearables for sleep, heart rate, and activity…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.