Dupont Lab

Boston Children's Hospital

Boston · United States

NIH-funded
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NIH R01 · 2024

Simple and Effective Laceration of Potentially-calcified Leaflets as an Adjunct to Transcatheter Valve Replacement

Project Summary Valvular heart disease is an important health problem afflicting over 2.5% of the US population and catheter- based therapies to address it have advanced significantly in recent years. While surgical repair remains the gold standard, the reduced risk of catheter-based interventions has provided the ability to intervene earlier in the disease process and in patients too sick for surgery while avoiding the risks of cardiopulmonary bypass. A significant limitation of these procedures, however, is that they do not provide the capability to remove native tissue and previously implanted devices to tailor the anatomy to receive a new prosthetic device. For example, transcatheter…

From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.

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