Dupont Lab

J. Craig Venter Institute, Inc.

La Jolla · United States

NIH-funded
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NIH R01 · 2025

Identifying Influenza Virus Infection Severity and Outcome Signatures Through Artificial Intelligence-driven Analyses

ABSTRACT Influenza and associated diseases remain significant sources of economic and public health burden. Every year, around three to five million people come down with severe cases of influenza with another 300,000 to 500,000 more who die worldwide. Amongst those who are disproportionately affected are individuals with chronic conditions such as diabetes, obesity, cardiovascular disease, children and individuals aged 65 years and older. For example, 90% of deaths from seasonal influenza and 70% of influenza-associated hospitalization belong to this age group. There is also a significant association between developing a heart attack within a week of getting infected with influenza A or B…

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