NIH R01 · 2025
Fatty Acid Modulation of Brain Function in Older Adults
Approaches to ameliorate cognitive decline with aging are few and often require behavioral changes that are difficult to maintain over long periods of time. The novel study proposed in this application will examine how manipulating dietary fatty acids affects brain functioning in older adults. Prior studies have shown that there are behavioral changes that can be made to improve cognition in adults on an acute time scale including improving sleep and physical activity. Based on preclinical data and our prior studies in humans we propose that brain functioning also can be acutely improved with a reduction in dietary saturated fat. We will use this approach in cognitively normal older adults…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.