NIH R01 · 2024
Reparative angiogenesis in ischemic retinopathy
Retinopathy of prematurity (ROP) is the leading cause of blindness in the U.S. and other developed countries in the pediatric population. A pivotal aspect of early ROP is retinal avascularity, which leads to advanced stages of ROP and pathologic retinal NV. Deficiency in vascularization of ischemic tissue is a major challenge in this disease condition. Current treatments for ROP are largely focused on later stages of disease characterized by pathologic pre-retinal neovascularization. These treatments are associated with significant side effects and do not address the retinal avascularity, which has an impact on the patient’s ultimate visual function. There is great need for early treatment,…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.