Cohen Lab

Vanderbilt University Medical Center

Nashville · United States

NIH-funded
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NIH R01 · 2024

Relational Memory as a Model of Behavioral (Dys)Function in Adults with Traumatic Brain Injury

Abstract Adults with traumatic brain injury (TBI) have deficits in flexible and goal-directed behavior and these impairments have been linked to negative outcomes and poor community reintegration and independence. The frontal lobes, and their putative functions of executive control and working memory, have figured prominently, and nearly exclusively, in mechanistic accounts of flexible and adaptive behavior and in understanding the underlying nature of behavioral dysfunction in individuals with TBI. Yet, interventions designed to target the frontal lobes have not yielded significant improvements in behavior or independence in the community. We propose that the frontal lobes may be the…

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