Dotson Lab

University of Texas at Austin

PSYCHIATRY

Austin · United States

NIH-funded
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Research focus

NIH R01 · 2024

Executive contributions to the “double jeopardy” of depressive symptoms and age on episodic memory in racially diverse adults

PROJECT SUMMARY/ABSTRACT Emerging evidence suggests that age and depression, even the modest levels common in aging, may interact to produce a “double jeopardy” for episodic memory impairment and may predict cognitive decline and Alzheimer’s disease (AD). The underlying cause/s of this double jeopardy is unknown. Even less is known about depression- related memory impairments in Black/African American and Mexican Americans, despite evidence of more disabling depression, and AD prevalence than in non-Hispanic Whites (NHWs). Multiple race-related proxy factors (e.g., discrimination, vascular burden, religiosity) that may exacerbate or reduce depression-related memory impairments but they have…

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