NIH R01 · 2025
Project Summary Schizophrenia (SZ) is a devastating psychiatric disorder that brings heavy burden to health care systems. A large literature indicates that individuals with SZ show markers of early aging, such as faster decline in cognitive functioning, increased risk for dementia, and significantly shorter life expectancies. Interestingly, the increased rate of dementia in SZ cannot be fully accounted for by the established dementia risk factors or the pathology of neurodegenerative disorders, suggesting additional pathological causes of cognitive impairment and increased mortality in older SZ patients. Additionally, many SZ patients develop medical conditions such as diabetes, metabolic…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.