NIH R01 · 2025
Physical aspects of Drosophila Gastrulation
The proper function of organisms, their organs, and their tissues requires them to have specific shape. How this shape is specified and maintained is a fundamental question in biology. In animals, the shape is determined through the process of morphogenesis, a concerted sequence of tissue remodeling events leading up to the final body plan. Despite a long-standing effort to understand the physical mechanisms that underlie morphogenesis, these mechanisms still remain largely unknown. Basic considerations from physics imply that in order to completely determine the mechanism of a morphogenetic change, two pieces of information are absolutely required: (1) material/mechanical properties of the…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.