NIH R01 · 2025
Reverse Metabolomics for the Discovery of Disease Associated Microbial Molecules
Project Summary/Abstract The Microbiota-Diet-Host interactions are critical to the balance of health and disease. Understanding this axis will be important to the development of nutritional precision medicine. Although there are some important discoveries where microbes make molecules that dramatically affect health, most of the molecules produced by microbiota still remain structurally uncharacterized. In addition, even when a molecule is known and the activity is known, this knowledge tends to be buried in papers and there is not a systematic organization of this knowledge that can be readily leveraged by data scientists. This prevents a deep mechanistic understanding of the microbiome.…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.