NIH R01 · 2024
Advancing Multi-bNAbs Microneedle Patch Technology For HIV-1 Prevention in Breastfeeding Infants.
PROJECT SUMMARY / ABSTRACT Despite significant progress made in preventing perinatal mother-to-child-transmission of HIV, 2022 saw about 130,000 new HIV infections in children globally, a vulnerable group that also accounts for 13% of AIDS-related deaths. Postnatal infection through breastfeeding remains a significant contributing factor for mother-to-child transmission of HIV, and often derives from untreated/undiagnosed mothers living with HIV or poor adherence to antiretrovirals (ARVs). Currently available prophylaxis options for newborns with the potential for perinatal exposure to HIV is ARV therapy. However, ARV formulations (oral and injectable) and regimens meant for pediatric use…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.