Dokras Lab

University of Pennsylvania

OBSTETRICS & GYNECOLOGY

Philadelphia · United States

NIH-funded
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Research focus

NIH R01 · 2025

Resistant starch treatment of polycystic ovary syndrome: impact on cardiometabolic dysfunction and the gut microbiome

Hyperandrogenic women with polycystic ovary syndrome (PCOS) have a high prevalence of cardiovascular disease (CVD) risk factors including obesity, insulin resistance, hypertension, and dyslipidemia that result in an increased risk of hypertensive disorders of pregnancy, type 2 diabetes and CVD events. Surveys also show significant dissatisfaction amongst women with PCOS regarding long-term counselling and management of their cardiometabolic risk. Although lifestyle interventions and oral contraceptive pills (OCPs) are recommended as first-line treatment for PCOS, there are no dietary or pharmacological recommendations for prevention of CVD risk in PCOS, indicating a considerable knowledge…

From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.

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