NIH R01 · 2024
Neural Circuits Balancing Reward-Approaching with Threat-Avoidance
PROJECT SUMMARY/ABSTRACT Although significant advances have been made in elucidating the structures that regulate fear and food- seeking responses in isolation, the neural circuits and mechanisms that integrate both behavioral responses remain poorly understood. Previous studies have shown that the paraventricular nucleus of the thalamus (PVT) is interconnected with areas of the brain implicated in the control of fear and food-seeking responses. We have recently shown that neurons in the anterior part of PVT (aPVT) respond differently to aversive and rewarding stimuli, suggesting that this region may be part of a core neural network that integrates fear and food-seeking responses. Using an…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.