Ding Lab

University of Pennsylvania

NEUROSCIENCES

Philadelphia · United States

NIH-funded
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NIH R01 · 2025

Neural mechanisms of flexible visual-oculomotor decision rules

PROJECT SUMMARY Visual decision-making in the brain is thought to depend on two behaviorally distinguishable computational components: one that converts uncertain visual inputs into a decision variable, and a second that applies a rule to the decision variable to commit to a choice. Our long-term goal is to understand the neural mechanisms that implement these computational components of high-order visual processing, which represent key building blocks of cognition. Here we propose to examine where and how visual decision rules are implemented in the brain. We build on three primary innovations: 1) a novel theoretical framework predicting that normative decision rules tend not to be static,…

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