NIH R01 · 2024
Gaze recovery during vestibular regeneration
PROJECT SUMMARY/ABSTRACT Gaze stabilization during head motion is a complex behavioral response that is highly dependent upon a functioning vestibular system. With vestibular loss, patients suffer gaze deficits that make it difficult to read, drive, or visually focus while moving throughout life. Remarkably, birds demonstrate complete spontaneous vestibular receptor regeneration following damage, unlike humans. In these animals, following regeneration, vestibular mediated gaze responses largely recover. However, the specific eye and head component responses that comprise gaze differ significantly following regeneration, suggesting that brain plasticity has re-wired the neural correlates…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.