NIH R01 · 2025
Robust detection of atrophy over short intervals in AD and FTLD
PROJECT SUMMARY Alzheimer’s disease, Frontotemporal Lobar Degeneration, and other diseases that lead to dementia are one of the 21st century’s major public health problems. This family of neurodegenerative diseases involves the disruption of functional brain circuits and ultimately the death of brain cells. In living people, the standard measure of neurodegeneration is derived from brain MRI scans, which can quantitatively measure the location and amount of atrophy. This is traditionally done, and continues to be done in many studies, over intervals of one year, with one or two scans collected one year apart, estimating annualized rates of brain atrophy. In some clinical trials, scans may…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.