NIH R01 · 2025
Consolidation and interference of hippocampal spatial maps
Project Summary Neurons throughout the brain remain highly active during sleep and produce complex patterns of action potentials. In unit recordings from the hippocampus, by comparing these patterns against earlier behavioral templates, numerous groups have shown that during hippocampal sharp-wave ripple (SWR) events these sleep patterns can correspond to replays of earlier experience. Additional research has further indicated that these SWR patterns play an important role in long term retention of memory. Developing and using advanced machine learning techniques and large-scale population recordings, we have recently demonstrated two remarkable phenomena during SWRs: that individual…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.