NIH R01 · 2024
Cervical, Anal & Oral HPV Persistence/Adolescent Girls
This application proposes continued study of a large and unique inner-city cohort of adolescent / young-adult women (AYA) conducted at Mount Sinai Adolescent Health Center (MSAHC) approximately 95% of whom are Black or Hispanic. We have shown the early quadrivalent (4v) HPV vaccine to be effective, despite some breakthrough infections by 4vHPV types. However, there remains a paucity of clinical study endpoints such as “breakthrough infections” of vaccine-HPV types, rates of non-vaccine high-risk HPV (hrHPV) types, and long- term HPV vaccine antibody titers. These data are important for determining whether HPV booster shots using the newer nonavalent (9v) HPV vaccine may be warranted for…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.