NIH R01 · 2025
Mechanisms for Deep Vein Thrombosis following Stroke
Project Summary/Abstract Venous thromboembolism (VTE), including deep vein thrombosis (DVT) and pulmonary embolism (PE) have an immense impact on morbidity and mortality. Acute ischemic stroke and aging are considered significant risk for developing life-threatening VTE events. While prophylactic anticoagulation reduces the rates of VTE in such high-risk patients, they only prevent approximately half of the expected VTE events and are associated with significant risk of bleeding, suggesting the critical need for novel and safe adjuvant treatments to reduce VTE burden. In recent years, compelling evidence has emerged that implicates neutrophils in the initiation and pathogenesis of deep vein…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.