Dhaka Lab

University of Washington

ANATOMY/CELL BIOLOGY

Seattle · United States

NIH-funded
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Research focus

NIH R01 · 2024

Identifying new targets in pain, utilizing the novel analgesic AS1

Project Summary Pain is the number one reason patients seek health care and greater than 20% of the US population is affected by chronic pain. Existing therapeutics have limited efficacy and a narrow therapeutic period, while also evoking deleterious side effects. It is therefore vital to understand pain processing in order to develop novel therapeutics to address this pressing health care crisis. According to the International Association for the Study of Pain (IASP) pain is “an unpleasant sensory and emotional experience associated with actual or potential tissue damage”. Intrinsic to the emotional suffering elicited by pain perception is the attribution of a negative valence to…

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