Donny Lab

Research focus

NIH R01 · 2025

Assessing the real-world impact of a low nicotine product standard for smoked tobacco in New Zealand

A low nicotine product standard for cigarettes and other combusted tobacco products has been proposed as a cornerstone of the FDA’s Comprehensive Plan for Tobacco and Nicotine Regulation in the United States (US). This proposed standard is based largely on randomized clinical trials demonstrating that when people switch to very low nicotine content (VLNC) cigarettes, cigarettes per day, dependence and biomarkers of smoke exposure decrease and quit attempts and cessation increase. Yet, these trials have important limitations. Notably, they limit the duration of exposure to VLNC cigarettes; cannot recreate the complex context of real-world product standards; are characterized by the use of…

From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.