NIH R01 · 2025
Metabolomics of ICH recovery (METABOL-ICH)
Project Summary: Stroke is the third leading cause of death and the leading cause of disability in the United States. Intracerebral hemorrhage (ICH) is the subtype of stroke with the highest morbidity and mortality and demonstrates marked race/ethnic differences. Specifically, Black Americans and Hispanic Americans demonstrate approximately double the incidence rate of ICH compared to people of European descent and have their hemorrhage an average 10 years earlier in life. ICH activates several metabolic pathways involving glycogen, sphingolipids, tryptophan/kynurenine, and others. Identifying the specific metabolites that are associated with poor outcomes would provide specific targets for…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.