Deluca Lab

Research focus

NIH R01 · 2024

Virus-cell interactions affecting HSV gene expression

PROJECT SUMMARY The ongoing theme of this program is to study the virus-cell interactions that affect HSV gene expression, with the primary focus on the mechanisms that regulate viral and cellular transcription during the course of infection. Progress during the last funding period has provided new insights into how the genes of HSV are transcribed in a regulated cascade during the course of viral infection. The studies also showed how viral processes and molecules can interact with and possibly regulate cellular transcription. We propose to extend on these studies and investigate new virus-cell interactions that affect virus and cell transcription. Ultimately, knowledge of how HSV genes…

From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.