NIH R01 · 2025
Epidemiologic identification and mechanistic investigation of early life environmental risk factors for eosinophilic esophagitis ABSTRACT Eosinophilic esophagitis (EoE) is a recently recognized immune-mediated disease defined by abnormal infiltration of eosinophils into the esophageal mucosa, leading to failure to thrive, abdominal pain, vomiting, and heartburn in children, and progressing to esophageal stenosis and food impaction in adults. Though initially thought to be rare, the incidence and prevalence are rising dramatically, and over the past decade EoE has rapidly become a major cause of upper gastrointestinal morbidity. Despite increases in the understanding of the condition, it is…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.