Delgado Lab

University of California, San Francisco

INTERNAL MEDICINE/MEDICINE

San Francisco · United States

NIH-funded
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NIH R01 · 2025

Contributions of Volume Overload Level and Ultrafiltration to Morbidity in ESKD

Project Summary/Abstract The long-term goal of this proposal is to modernize clinical methods for assessing fluid excess for removal during in-center hemodialysis treatment using newer assessment techniques. The experience of trial-and-error assessment of a “dry weight,” a weight at which a patient can tolerate fluid removal without the development of symptoms of hypovolemia or hypervolemia, a common practice for over 50 years, that may have a lasting effect on the ability to function for nearly 500,000 Americans who depend on hemodialysis for survival. Newer techniques for quantifying excess extracellular volume for removal during hemodialysis do exist. Small studies have suggested the…

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