NIH R01 · 2024
In vivo ACL mechanics and risk factors for injury
Abstract An estimated 400,000 anterior cruciate ligament (ACL) injuries occur yearly in the United States. Most ACL injuries are non-contact, occurring during rapid deceleration movements such as jumping and cutting. Importantly, the risk of early-onset osteoarthritis (OA) persists regardless of whether ACL reconstruction is performed. Therefore, identifying risk factors for non-contact ACL injury is of great clinical importance. The function of the ACL is to resist tibiofemoral motion during the intense forces associated with dynamic activity. Therefore, measuring the dynamic elongation patterns of the ACL functional bundles will provide imaging biomarkers of elevated tension within the…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.