Deelchand Lab

University of Minnesota

RADIATION-DIAGNOSTIC/ONCOLOGY

Minneapolis · United States

NIH-funded
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NIH R01 · 2024

Fully Automated Motion-corrected MR Spectroscopy in Human Brain and Spinal Cord

PROJECT SUMMARY/ABSTRACT Proton magnetic resonance spectroscopy (1H MRS) and spectroscopic imaging (MRSI) allow noninvasive study of brain chemistry. However, subject motion remains a major obstacle in MRS, especially in motion-prone populations such as children, the elderly, and patients with movement disorders. Motion results in inaccurate localization and degrades MRS spectral quality. Most of these effects cannot be corrected retroactively, and must be corrected prospectively (i.e. in real-time). In the brain, existing prospective motion-corrected MRS sequences are currently limited to a handful of research centers and are not widely used. In the spinal cord, prospective motion and shim…

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