NIH R01 · 2024
Abstract: Progressive difficulty in performing everyday functional activities is a key diagnostic feature of dementia syndromes. However, not much is known about the neural signature of functional decline, particularly during the very early stages of dementia. Early intervention before overt impairment is observed offers the best hope of reducing the burdens of Alzheimer’s disease and other dementias. But to justify early intervention, those at risk need to be detected earlier and more accurately. Decline in complex daily function (CdF) such as managing medications has been reported to precede impairment in basic activities of daily living (e.g., eating, dressing). Our goal is to establish…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.