NIH R01 · 2024
Project Summary Despite therapeutic advances, ~20% of patients with hypertension have uncontrolled high blood pressure, a condition that is associated with dysfunction in brain cardiovascular control centers. Therefore, there is a critical need to understand the neural pathways involved in cardiovascular regulation and how their dysfunction contributes to high blood pressure. This is particularly important for hypertension that is induced by chronic social stress, a major problem in today’s world, which involves activation of neuroendocrine and autonomic mechanisms. Our previous studies using novel genetic mouse models, viral-mediated gene transfer and optogenetics have revealed angiotensin…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.