De Boer Lab

University of Washington

INTERNAL MEDICINE/MEDICINE

Seattle · United States

NIH-funded
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Research focus

NIH R01 · 2025

Blood Sugar Sensing on Maintenance Dialysis

ABSTRACT Hyperglycemia is the cardinal manifestation of diabetes mellitus and an established risk factor for kidney failure, retinopathy, neuropathy, and cardiovascular disease in the general diabetes population. However, with dialysis, measurement and management of glycemia is notoriously difficult, due in part to known inaccuracies of hemoglobin A1c. In addition, severe hypoglycemia is common in dialysis patients with and without diabetes. As a result, relationships of glycemia with clinical outcomes and unique determinants of glycemia are poorly defined in the dialysis population. These knowledge gaps preclude development of informed therapeutic strategies. We initiated the BLOod Sugar…

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