NIH R01 · 2025
Adults with Fragile X Syndrome: Health and Life Course Trajectories
This is a continuation application for an additional 5 years of support for a comparative and prospective study of Fragile X Syndrome (FXS), an inherited neurodevelopmental disorder caused by a trinucleotide expansion of CGG repeats in the FMR1 gene on the X chromosome. FXS results in significant health and functional impairments that begin in early childhood and last a lifetime. It is the most common inherited cause of intellectual disability and autism, with substantial family burden and public health impacts. Critically, the great majority of knowledge about the FXS clinical phenotype derives from research on children, leaving adulthood a vast uncharted territory. The purpose of the…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.