NIH R01 · 2024
Optimized Intracranial EEG Targeting in Focal Epilepsy based upon Neuroimaging Connectomics
Despite recent advances in neuroimaging, approximately 2/3 of intractable epilepsy patients that undergo surgical evaluation continue to require intracranial EEG (IEEG), arguably the most invasive diagnostic test in medicine. We currently lack methods to quantitatively map noninvasive imaging measures of structure and function to IEEG. Specifically, there is a critical need to validate whole-brain noninvasive neuroimaging network- based biomarkers to guide precise placement of electrodes and translate noninvasive network neuroimaging to change the paradigms of clinical care. The long-term goal of this proposal is to predict IEEG functional dynamics and surgical outcomes using noninvasive…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.