NIH R01 · 2025
Project Summary Hematopoietic stem cell transplant (HSCT) is increasingly used for non-malignant hematologic disorders such as sickle cell anemia and marrow failure, and complications of HSCT are more prevalent and important as causes of long term morbidity. Improved diagnosis and treatment and treatment are urgent issues. Lung injury is frequent after HSCT, with as many as 15% of children transplanted having reduced FEV1, later leading to overt bronchiolitis obliterans (BO) which is associated with high morbidity and mortality. Diagnosis of BO in adults depends on spirometry, and evidence suggests that early diagnosis may improve chances of recovery of lung function and survival. Small…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.