Damon Lab

Carle Foundation

Urbana · United States

NIH-funded
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NIH R01 · 2024

Development and Application of Muscle Diffusion Tensor MRI

PROJECT SUMMARY We will advance the quantitative understanding of how human muscle structure impacts function, in health and disease; and we will share the magnetic resonance imaging (MRI) resources used to generate this knowledge freely with the muscle research community. At every level of biological complexity, muscle structure significantly influences muscle function. These properties include the intermediate-scale relationships known as muscle architecture: the shape and orientation of a muscle’s fibers with respect to its mechanical line of action. Our understanding of how muscle architecture affects muscle function remains incomplete, however, and our tools for studying these…

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