Damania Lab

Univ of North Carolina Chapel Hill

MICROBIOLOGY/IMMUN/VIROLOGY

Chapel Hill · United States

NIH-funded
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NIH R01 · 2025

Therapy for Non-Hodgkin lympoma

Abstract Viruses are the etiological agents of a number of different human cancers. Epstein-Barr virus (EBV) is a ubiquitous pathogen infecting over 95% of the human population worldwide. EBV is the etiological agent of several malignancies including Hodgkin lymphoma (HL), and multiple types of non-Hodgkin lymphoma (NHL) including post-transplant lymphoproliferative disease (PTLD), diffuse large B cell lymphomas (DLBCL), T cell lymphomas, NK/T cell lymphoma (NKTL), and Burkitt's lymphoma (BL). In addition, EBV is also associated with nasopharyngeal carcinoma (NPC) and gastric cancer. There is an increased incidence of EBV-associated NHL in HIV-infected patients. HIV-positive individuals…

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