NIH R01 · 2024
Cervical Epidural Stimulation and Respiratory Motor Plasticity
Project Summary More than half of traumatic spinal cord injuries (SCI) occur at the cervical level, leading to paralysis and respiratory compromise or failure. Approximately 20% of cSCI patients will require ventilator support for which there are very few therapeutic options for recovery. Epidural stimulation has emerged as a strategy to restore a variety of motor, sensory, and autonomic functions in both experimental and clinical conditions after SCI. Though limited underlying mechanisms have been proposed, to date little is known how epidural stimulation elicits motor function at the neuronal level. Even less is known about the capacity for epidural stimulation to promote long-lasting…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.