Benowitz Lab

University of Nebraska Medical Center

BIOSTATISTICS & OTHER MATH SCI

Omaha · United States

NIH-funded
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NIH R01 · 2024

Health Effects of E-cigarette Use on Brain Functions and Cognitive Development among Adolescents: A US Population-Based Study

Project Summary Electronic Nicotine Delivery System (ENDS) use has been a major public health concern. The U.S. Food and Drug Administration (FDA) continues to cite health effects as a chief rationale in FDA enforcement priorities and marketing denials. Childhood to adolescence represents a critical period with rapid development in brain maturation. Combustible cigarette smoking during adolescence can negatively impact brain development, and animal models also show that nicotine exposure in adolescent rodents slows brain maturation, including the prefrontal cortex. However, the impact of rising ENDS use on youth brain functions and cognitive outcomes is poorly understood. Vaping delivers…

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