Dacey Lab

University of Washington

ANATOMY/CELL BIOLOGY

Seattle · United States

NIH-funded
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Research focus

NIH R01 · 2025

Synaptic Architecture and Mechanisms of Direction Selectivity in Primate Retina

A major research challenge for neurobiology is to understand the neural mechanisms that give rise to an extreme diversity of parallel visual pathways and ultimately the contributions that these pathways make to our perception of motion, form and color. For motion perception the cell types, circuits and synaptic mechanisms that mediate selectivity to the direction of moving stimuli have been intensively studied in the non-primate mammal for decades and over a dozen distinct direction selective pathways are recognized in the mouse retina together with growing evidence for similarly diverse underlying neural mechanisms. The great complexity of the visual pathways found in the mouse is mirrored…

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